Trentina Di Muccio Selected Research

trypanothione

2/2020	Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism.
11/2018	Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening.

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Trentina Di Muccio Research Topics

Disease

5	Leishmaniasis 02/2020 - 03/2011
4	Infections 02/2020 - 08/2012
1	Ulcer 01/2021
1	Mucocutaneous Leishmaniasis 08/2020
1	Hypersensitivity (Allergy) 12/2019
1	HIV Infections (HIV Infection) 12/2019
1	Spotted Fever Group Rickettsiosis (Rickettsialpox) 05/2019
1	Visceral Leishmaniasis (Kala Azar) 09/2008
1	Acute Kidney Injury (Acute Renal Failure) 09/2008
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 09/2008

Drug/Important Bio-Agent (IBA)

4	liposomal amphotericin B FDA Link 01/2021 - 09/2008
2	Meglumine AntimoniateIBA 01/2021 - 08/2020
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 02/2020 - 11/2018
2	trypanothioneIBA 02/2020 - 11/2018
2	tryparedoxinIBA 02/2020 - 11/2018
2	tryparedoxin peroxidaseIBA 02/2020 - 11/2018
2	trypanothione reductaseIBA 02/2020 - 11/2018
2	EnzymesIBA 02/2020 - 11/2018
2	Pharmaceutical PreparationsIBA 08/2012 - 03/2011
1	AzolesIBA 08/2020
1	Pentamidine (NebuPent)FDA LinkGeneric 08/2020
1	Sulfides (Thioethers)IBA 02/2020
1	miltefosine (Impavido)IBA 12/2019
1	DNA (Deoxyribonucleic Acid)IBA 05/2019
1	Leishmaniasis VaccinesIBA 10/2014
1	VaccinesIBA 10/2014
1	SilverIBA 03/2011
1	AntimonyIBA 03/2011

Therapy/Procedure

1	Therapeutics 01/2021